*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE6160000
CHEMICAL NAME           : Ergoline-8-beta-carboxamide,
                          9,10-didehydro-N,N,6-trimethyl-
CAS REGISTRY NUMBER     : 4238-84-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H21-N3-O
MOLECULAR WEIGHT        : 295.42
WISWESSER LINE NOTATION : T C6656 1A P GN LM
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * DAM-57
   * 9,10-Didehydro-N,N,6-trimethylergoline-8-beta-carboxamide
   * N,N-Dimethyllysergamide
   * Lysergamide, N,N-dimethyl-
   * d-Lysergic acid dimethylamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 10 ug/kg
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
   Behavioral - toxic psychosis
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   PSYPAG Psychopharmacologia (Berlin).  (Berlin, Ger.)  V.1-46, 1959-76.  For
   publisher information, see PSCHDL.  Volume(issue)/page/year: 1,20,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,95,1972
 
                            *** END OF RECORD ***