*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE6170000
CHEMICAL NAME           : Ergoline-8-carboxamide,
                          N-(1,1-dimethylethyl)-6-methyl-, (8-beta)-,
                          (Z)-2-butenedioate (1:1)
CAS REGISTRY NUMBER     : 50504-28-4
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H27-N3-O.C4-H4-O4
MOLECULAR WEIGHT        : 441.58
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (8-beta)-N-(1,1-Dimethylethyl)-6-methylergoline-8-carboxamide  
   (Z)-2-butenedioate (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 62,1881,1973
 
                            *** END OF RECORD ***