*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE6338150
CHEMICAL NAME           : Ergoline-8-ethanamine, N-ethyl-6-methyl-, (8-beta)-,
                          (Z)-2-butenedioate (1:2)
CAS REGISTRY NUMBER     : 59033-49-7
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H27-N3.2C4-H4-O4
MOLECULAR WEIGHT        : 529.65
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * (8-beta)-N-Ethyl-6-methylergoline-8-ethanamine (Z)-2-butenedioate (1:2)
   * D-6-Methyl-8-(beta-ethylaminoethyl)ergoline-I bis(hydrogen maleate)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4450 ug/kg
SEX/DURATION            : female 1-5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,2765,1976
 
                            *** END OF RECORD ***