*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : KG2940000 CHEMICAL NAME : Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxy -1-propenyl)-, (11-beta,17-beta,17(Z))- CAS REGISTRY NUMBER : 97747-88-1 BEILSTEIN REFERENCE NO. : 5663600 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C29-H37-N-O3 MOLECULAR WEIGHT : 447.67 COMPOUND DESCRIPTOR : Drug Reproductive Effector Hormone SYNONYMS/TRADE NAMES : * ZK 98.734 *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 1250 ug/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 40,549,1989 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 45 mg/kg SEX/DURATION : female 5-7 day(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - other effects Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - other measures of fertility REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 83,73,1988 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Primate - monkey DOSE : 37500 ug/kg SEX/DURATION : female 24-26 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 38,528,1988 *** END OF RECORD ***