*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KG4550000
CHEMICAL NAME           : Estradiol, 17-caprylate
CAS REGISTRY NUMBER     : 63042-22-8
BEILSTEIN REFERENCE NO. : 3168440
REFERENCE               : 3-06-00-05347 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H38-O3
MOLECULAR WEIGHT        : 398.64
WISWESSER LINE NOTATION : L E5 B666TTT&J E FOV7 OQ
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Caprylate d'oestradiol
   * Estra-1,3,5(10)-triene-3,17beta-diol 17-octanoate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 800 ug/kg/13W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 130,1466,1939
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2800 ug/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   RCBIAS Revue Canadienne de Biologie.  (Montreal, Quebec, Canada)  V.1-40,
   1942-81.  Volume(issue)/page/year: 3,108,1944
 
                            *** END OF RECORD ***