*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KG7395000
CHEMICAL NAME : Estra-1,3,5(10)-triene-16-alpha,17-beta-diol,
3-(cyclopentyloxy)-
CAS REGISTRY NUMBER : 1169-79-5
LAST UPDATED : 198910
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C23-H32-O3
MOLECULAR WEIGHT : 356.55
WISWESSER LINE NOTATION : L E5 B666TTT&J E1 FQ GQ OO- AL5TJ
COMPOUND DESCRIPTOR : Drug
Reproductive Effector
Hormone
SYNONYMS/TRADE NAMES :
* Colpovis
* Colpovister
* 3-(Cyclopentyloxy)estra-1,3,5(10)-triene-16-alpha,17-beta-diol
* Estra-1,3,5(10)-triene-16,17-diol, 3-(cyclopentyloxy)-,
(16-alpha,17-beta)-
* Estriol cyclopentyl ether
* Estriol 3-cyclopentyl ether
* Estriolo 3-etere ciclopentilico
* Pentovis
* Quinestradiol
* Quinestradol
* Quinestradolo
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 713 ug/kg
SEX/DURATION : female 16-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
AOGMAU Annali di Ostetricia, Ginecologia, Medicina Perinatale. (Istiuti
Clinica di Perfezionamento di Milano, Via Daverio, 6, 20122 Milan, Italy)
V.93- 1972- Volume(issue)/page/year: 96,83,1975
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 500 ug/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
STEDAM Steroids. (Holden-Day Inc., 4432 Telegraph Ave., Oakland, CA 94609)
V.1- 1963- Volume(issue)/page/year: 20,223,1972
*** END OF RECORD ***