*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KG7675000
CHEMICAL NAME           : Estra-1,3,5(10)-triene-2,3,17-beta-triol
CAS REGISTRY NUMBER     : 362-05-0
BEILSTEIN REFERENCE NO. : 2219367
REFERENCE               : 4-06-00-07547 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H24-O3
MOLECULAR WEIGHT        : 288.42
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 2-Hydroxyestradiol
   * 2-OH-Estradiol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1280 ng/kg
SEX/DURATION            : male 8 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - other effects on male
   Endocrine - androgenic
REFERENCE :
   ANDRDQ Andrologia.  (Grosse Verlag GmbH, Kurfuerstenstr. 112-113, D-1000
   Berlin 30, Fed. Rep. Ger.) V.6-    1974-  Volume(issue)/page/year:
   23,339,1991
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 42,165,1986
 
                            *** END OF RECORD ***