*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : KH8587500 CHEMICAL NAME : 1,2-Ethanediamine, N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5- naphthyridin-10- yl)-, dihydrochloride CAS REGISTRY NUMBER : 38915-24-1 LAST UPDATED : 199410 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H18-Cl2-N4-O.2Cl-H MOLECULAR WEIGHT : 438.21 WISWESSER LINE NOTATION : T C666 BN GNJ FO1 IM2M2G MG &GH 2 COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * 7-Chloro-10-((2-((2-chloroethyl)amino)ethyl)amino)-2-methoxybenzo(b)-1,5 -naphthyridine 2HCl * ICR 364 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD20 - Lethal Dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 263 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,739,1972 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 5 ug/plate REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,739,1972 *** END OF RECORD ***