*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KH8588700
CHEMICAL NAME           : 1,2-Ethanediamine,
                          N'-(6-chloro-2-methoxy-9-acridinyl)-N-(2-chloropropyl
                          )-, dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 38915-20-7
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H21-Cl2-N3-O.2Cl-H.H2-O
MOLECULAR WEIGHT        : 468.26
WISWESSER LINE NOTATION : T C666 BNJ EG IM2M1YG1 LO1 &GH 2 &QH
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Acridine, 6-chloro-9-((2-((2-chloropropyl)amino)ethyl)amino)-2-methoxy-,  
   2HCl, hydrate
   * 6-Chloro-9-((2-((2-chloropropyl)amino)ethyl)amino)-2-methoxyacridine  
   dihydrochloride hydrate
   * ICR 443
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 141 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 ug/plate
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            *** END OF RECORD ***