*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KI1425000
CHEMICAL NAME           : Ethane, 2,2-difluoro-1,1,1,2-tetrachloro-
CAS REGISTRY NUMBER     : 76-11-9
BEILSTEIN REFERENCE NO. : 1699461
REFERENCE               : 4-01-00-00146 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 26
MOLECULAR FORMULA       : C2-Cl4-F2
MOLECULAR WEIGHT        : 203.82
WISWESSER LINE NOTATION : GXGGXGFF
SYNONYMS/TRADE NAMES :
   * CFC 112a
   * 1,1-Difluoroperchloroethane
   * 1,1-Difluoro-1,2,2,2-tetrachloroethane
   * F 112a
   * Halocarbon 112a
   * R 112a
   * Refrigerant 112a
   * 1,1,1,2-Tetrachloro-2,2-difluoroethane
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 210,744,1966
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20000 ppm/30M
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - somnolence (general depressed activity)
   Liver - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   19,1,1971

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 4170 mg/m3 (500 ppm)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 500 ppm (4170 mg/m3)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,249,1971

   OSHA PEL (Gen Indu):8H TWA 500 ppm (4170 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 500 ppm (4170 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 500 ppm (4170 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 500 ppm (4170 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 500 ppm (4170 mg/m3) JAN 1993
   
   OEL-BELGIUM:TWA 500 ppm (4170 mg/m3) JAN 1993
   
   OEL-DENMARK:TWA 500 ppm (4170 mg/m3) JAN 1993
   
   OEL-FINLAND:TWA 500 ppm (4170 mg/m3);STEL 625 ppm (5215 mg/m3) JAN 1993
   
   OEL-FRANCE:TWA 500 ppm (4170 mg/m3) JAN 1993
   
   OEL-GERMANY:TWA 1000 ppm (8340 mg/m3) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 500 ppm (4170 mg/m3) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 500 ppm (4170 mg/m3) JAN 1993
   
   OEL-SWITZERLAND:TWA 500 ppm (4200 mg/m3) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 100 ppm (834 mg/m3);STEL 100 ppm JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO 1,1,1,2-TETRACHLORO-2,2-DIFLUOROETHANE-air:TWA 500 ppm
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: 1,1,1,2-Tetrachloro-2,2-difluoroethane, 1016
   
   NIOSH Analytical Method, 1996: 1,1,2,2-Tetrachloro-1,2-difluoroethane, 1016

 
                            *** END OF RECORD ***