*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KI1435000
CHEMICAL NAME           : Ethane, 1,1-difluoro-1,2,2-trichloro-
CAS REGISTRY NUMBER     : 354-21-2
BEILSTEIN REFERENCE NO. : 1736764
REFERENCE               : 4-01-00-00141 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C2-H-Cl3-F2
MOLECULAR WEIGHT        : 169.38
WISWESSER LINE NOTATION : GYGXGFF
SYNONYMS/TRADE NAMES :
   * F 122 (halocarbon)
   * FC 122
   * Freon 122
   * Frigen 122
   * HCFC 122
   * R 122
   * 1,1,2-Trichloro-2,2-difluoroethane
   * 1,2,2-Trichloro-1,1-difluoroethane
   * Ucon fluorocarbon 122
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HXPHAU Handbuch der Experimentellen Pharmakologie.  (Berlin, Ger.)  New
   series: V.1-49, 1935-78. For publisher information, see HEPHD2.
   Volume(issue)/page/year: 20(Pt 1),459,1966
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCMH** Union Carbide Manual Hazard Sheet.  (Industrial Medicine & Toxicology
   Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017)
   Volume(issue)/page/year: 15NOV1962
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 ppm/6H/2W-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - other changes in urine composition
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   INHTE5 Inhalation Toxicology.  (Hemisphere Publishing Corp., c/o Taylor &
   Francis Inc., 1900 Frost Rd., Suite 101, Bristol, PA 19007)  V.1-    1989-
   Volume(issue)/page/year: 4,81,1992

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***