*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KI2625000
CHEMICAL NAME           : 1,2-Ethanediol, 1-phenyl-, 2-carbamate
CAS REGISTRY NUMBER     : 94-35-9
BEILSTEIN REFERENCE NO. : 1874189
REFERENCE               : 4-06-00-05941 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C9-H11-N-O3
MOLECULAR WEIGHT        : 181.21
WISWESSER LINE NOTATION : ZVO1YQR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AL 1076
   * Carbamic acid, beta-hydroxyphenethyl ester
   * beta-Hydroxyphenethyl carbamate
   * 2-Hydroxy-2-phenylethyl carbamate
   * Linaxar
   * Myospaz
   * Phenethyl alcohol, beta-hydroxy-, alpha-carbamate
   * 1-Phenyl-1,2-ethanediol 2-carbamate
   * 2-Phenyl-2-hydroxyethyl carbamate
   * Sinaxar
   * Stiramato
   * Styramate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 126,318,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1240 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 126,318,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,264,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 126,318,1959
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 65 gm/kg/13W-C
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 126,318,1959
 
                            *** END OF RECORD ***