*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : KI2625000 CHEMICAL NAME : 1,2-Ethanediol, 1-phenyl-, 2-carbamate CAS REGISTRY NUMBER : 94-35-9 BEILSTEIN REFERENCE NO. : 1874189 REFERENCE : 4-06-00-05941 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C9-H11-N-O3 MOLECULAR WEIGHT : 181.21 WISWESSER LINE NOTATION : ZVO1YQR COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * AL 1076 * Carbamic acid, beta-hydroxyphenethyl ester * beta-Hydroxyphenethyl carbamate * 2-Hydroxy-2-phenylethyl carbamate * Linaxar * Myospaz * Phenethyl alcohol, beta-hydroxy-, alpha-carbamate * 1-Phenyl-1,2-ethanediol 2-carbamate * 2-Phenyl-2-hydroxyethyl carbamate * Sinaxar * Stiramato * Styramate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 126,318,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1240 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 126,318,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,264,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 126,318,1959 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 65 gm/kg/13W-C TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 126,318,1959 *** END OF RECORD ***