*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KJ4110010
CHEMICAL NAME           : Ethane, 1,1,2-trifluoro-
CAS REGISTRY NUMBER     : 430-66-0
BEILSTEIN REFERENCE NO. : 1731624
REFERENCE               : 4-01-00-00123 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C2-H3-F3
MOLECULAR WEIGHT        : 84.05
SYNONYMS/TRADE NAMES :
   * FC 143
   * R 143
   * 1,1,2-Trifluoroethane
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 25 gm/m3/6H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(10),21,1964
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 25 gm/m3/4H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(10),21,1964
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/m3/4H/17W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(10),21,1964
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/m3/4H/17W-I
TOXIC EFFECTS :
   Behavioral - alteration of classical conditioning
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Blood - changes in spleen
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(10),21,1964
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 mg/m3/4H/17W-I
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Liver - changes in liver weight
   Endocrine - changes in thyroid weight
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(10),21,1964
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 50 mg/m3/4H/17W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(10),21,1964

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0493-8884S
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***