*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KJ8925000
CHEMICAL NAME           : Ethanol, 2-butoxy-, acetate
CAS REGISTRY NUMBER     : 112-07-2
BEILSTEIN REFERENCE NO. : 1756960
REFERENCE               : 4-02-00-00215 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 18
MOLECULAR FORMULA       : C8-H16-O3
MOLECULAR WEIGHT        : 160.24
WISWESSER LINE NOTATION : 4O2OV1
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Acetic acid, 2-butoxyethyl ester
   * 2-Butoxyethanol acetate
   * 2-Butoxyethyl acetate
   * 2-Butoxyethylester kyseliny octove
   * Butyl cellosolve acetate
   * Butylcelosolvacetat
   * Butylglycol acetate
   * Ektasolve EB acetate
   * Ethylene glycol monobutyl ether acetate
   * Glycol monobutyl ether acetate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg
REACTION SEVERITY       : Mild
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 1/31/1966
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,713,1986
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - hematuria
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   51,117,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KODAK* Kodak Company Reports.  (343 State St., Rochester, NY 14650)
   Volume(issue)/page/year: 21MAY1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - hematuria
   Kidney, Ureter, Bladder - other changes in urine composition
   Blood - normocytic anemia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   51,117,1979
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 5 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KODAK* Kodak Company Reports.  (343 State St., Rochester, NY 14650)
   Volume(issue)/page/year: 21MAY1971

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRIA:TWA 20 ppm (135 mg/m3) JAN 1993
   
   OEL-GERMANY:TWA 20 ppm (135 mg/m3);Skin JAN 1993
   
   OEL-THE NETHERLANDS:TWA 20 ppm (135 mg/m3);STEL 40 ppm;Skin JAN 1993
   
   OEL-SWITZERLAND:TWA 20 ppm (135 mg/m3);STEL 40 ppm;Skin JAN 1993
   
   OEL-UNITED KINGDOM:TWA 10 ppm (54 mg/m3);Skin JAN 1993
   
   OEL-UNITED KINGDOM:TWA 5 ppm (24 mg/m3);Skin JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO EGBEA-air:10H TWA 5 ppm (Sk)
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81350
       No. of Facilities: 4676 (estimated)
       No. of Industries: 50
       No. of Occupations: 41
       No. of Employees: 36527 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81350
       No. of Facilities: 15329 (estimated)
       No. of Industries: 116
       No. of Occupations: 70
       No. of Employees: 150893 (estimated)
       No. of Female Employees: 38379 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***