*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KK2810000
CHEMICAL NAME           : Ethanol, 2-chloro-, phosphite (3:1)
CAS REGISTRY NUMBER     : 140-08-9
BEILSTEIN REFERENCE NO. : 1704979
REFERENCE               : 4-01-00-01378 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 11
MOLECULAR FORMULA       : C6-H12-Cl3-O3-P
MOLECULAR WEIGHT        : 269.50
WISWESSER LINE NOTATION : G2OPO2GO2G
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 2-Chloroethanol phosphite (3:1)
   * Phosphorous acid, tris(2-chloroethyl) ester
   * Tris(2-chloroethyl)ester of phosphorus acid
   * Tris(2-chloroethyl)phosphite
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ALBRW* Albright & Wilson Inc.  (P.O. Box 26229, Richmond, VA 23260-6229)
   Volume(issue)/page/year: #OPB-3,1984
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 2,184,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 810 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ALBRW* Albright & Wilson Inc.  (P.O. Box 26229, Richmond, VA 23260-6229)
   Volume(issue)/page/year: #OPB-3,1984
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 21 gm/kg/2D-I
TOXIC EFFECTS :
   Blood - hemorrhage
   Skin and Appendages - dermatitis, other (after systemic exposure)
   Related to Chronic Data - death
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0536380
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 333 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5(Suppl
   1),3,1983

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   47,26992,82

   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8863;8EHQ-0892-9131
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9259
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***