*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KL5090000
CHEMICAL NAME           : Ethanol, 2-(isopropylamino)-, hydrochloride
CAS REGISTRY NUMBER     : 54472-62-7
LAST UPDATED            : 198910
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C5-H13-N-O.Cl-H
MOLECULAR WEIGHT        : 139.65
WISWESSER LINE NOTATION : Q2MY1&1 &GH
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Isopropylamino ethanol hydrochloride
   * 2-(Isopropylamino)ethanol hydrochloride
   * PAE
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 434 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 442 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 150 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 250 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 200 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 120 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 40 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 42,319,1975
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 20 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 42,319,1975
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 200 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   TIYADG Tianjin Yiyao.  Tianjin Medical Journal.  (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China)  V.1-    1973-
   Volume(issue)/page/year: 9,553,1981
 
                            *** END OF RECORD ***