*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KJ4550000
CHEMICAL NAME           : 9,10-Ethanoanthracene-9-(10H)-methylamine, N-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 10085-81-1
LAST UPDATED            : 199506
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H19-N.Cl-H
MOLECULAR WEIGHT        : 285.84
WISWESSER LINE NOTATION : L6 H666/GP 2AF P&&TTJ G1M1 &GH
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * BA 30,803
   * Benzoctamine hydrochloride
   * N-Methylethanoanthracene-9-(10H)-methylamine hydrochloride
   * 1-Methylaminomethyldibenzo(b,c)bicyclo(2,2,2)octadiene hydrochloride
   * Tacitin
   * Tracitin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 26 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,336,1972
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 51 mg/kg
SEX/DURATION            : female 2-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - eye/ear
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale.  (Casa
   Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy)  V.2- 1927- 
   Volume(issue)/page/year: 49,1309,1973
 
                            *** END OF RECORD ***