*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KL9400000
CHEMICAL NAME           : Ethanol, 2,2'-nitroiminodi-, dinitrate (ester)
CAS REGISTRY NUMBER     : 4185-47-1
BEILSTEIN REFERENCE NO. : 1803252
REFERENCE               : 4-04-00-03414 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C4-H8-N4-O8
MOLECULAR WEIGHT        : 240.16
WISWESSER LINE NOTATION : WNO2NNW2ONW
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Diethanolnitramine dinitrate
   * Diethanol-N-nitramine dinitrate
   * DINA
   * 2,2'-Dinitrato-N-nitrodiethylamine
   * sym-Dinitroxydiethylnitramine
   * Ethanol, 2,2'-(nitroimino)bis-, dinitrate (ester)
   * Nitrodiethanolamine dinitrate
   * N-Nitrodiethanolamine dinitrate
   * 2,2'-Nitroiminobis(ethylnitrate)
   * 2,2'-(Nitroimino)bisethanol dinitrate (ester)
   * 2,2'-Nitroiminodiethanol nitrate
   * 2,2'-(Nitroimino)ethanol dinitrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3360 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KHZDAN Khigiena i Zdraveopazvane.  Hygiene and Sanitation.  (Hemus, Blvd.
   Russki 6, Sofia, Bulgaria) V.9-    1966-  Volume(issue)/page/year: 9,50,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 10,1504,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 8,565,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 8,565,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 8,565,1953
 
                            *** END OF RECORD ***