*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RJ7800000
CHEMICAL NAME           : 3,5-Ethano-2H-furo(2,3-o)(2)benzoxacycloundecin-13-ca
                          rboxylic acid,
                          3,3a,5,6,7,8,9,10,11,11a,14,15-dodecahydro-2,17-dioxo
                          -16-methylene-3,6,8,1 4-tetramethyl-,
                          (3R-(3R*,3aR*,5R*,6R*,8R*,11aS*,14S*,15aS*))-
CAS REGISTRY NUMBER     : 111367-04-5
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H32-O6
MOLECULAR WEIGHT        : 416.56
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Okilactomycin
   * YP-02908L-A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 40,1475,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 40,1475,1987
 
                            *** END OF RECORD ***