*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KM5300000
CHEMICAL NAME           : Ethanol,
                          2-((2-(4-(3,3,3-trifluoro-1,2-diphenyl-1-propenyl)phe
                          noxy)ethyl)amino)-, (E)-
CAS REGISTRY NUMBER     : 77599-17-8
LAST UPDATED            : 198602
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H24-F3-N-O2
MOLECULAR WEIGHT        : 427.50
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (E)-1,2-Diphenyl-1-(4-((2-hydroxyethylamino)ethoxy)phenyl)-3,3,3-trifluo
     ro-1-propene
   * GYKI-13504
   *   (E)-2-((2-(4-(3,3,3-Trifluoro-1,2-diphenyl-1-propenyl)phenoxy)ethyl)amin
     o)ethanol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,395,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,395,1985
 
                            *** END OF RECORD ***