*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KM8100000
CHEMICAL NAME : 6,14-endo-Ethenotetrahydrooripavine,
7-alpha-(1-hydroxy-1-methylbutyl)-
CAS REGISTRY NUMBER : 14521-96-1
LAST UPDATED : 198910
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C25-H33-N-O4
MOLECULAR WEIGHT : 411.59
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* 7,8-Dihydro-7-alpha-(1-(R)-hydroxy-1-methylbutyl)-O(sup
6)-methyl-6,14-endo-ethenomorphine
* Etorphine
* (-)-Etorphine
* 7-alpha-Etorphine
* 7-alpha-(1-(R)-Hydroxy-1-methylbutyl)-6,14-endo-ethenotetrahydrooripavine
* Oripavine, 6,14-endo-ethylenetetrahydro-7-(1-hydroxy-1-methylbutyl)-
* 19-Propylorvinol
* Tetrahydro-7-alpha-(1-hydroxy-1-methylbutyl)-6,14-endo-ethenooripavine
* Tetrahydro-7-alpha-(2-hydroxy-2-pentyl)-6,14-endo-ethenooripavine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser
Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70-
Volume(issue)/page/year: 6,755,1976
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 3200 ng/kg
SEX/DURATION : male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - other effects on male
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 198,340,1976
*** END OF RECORD ***