*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : KN0350000 CHEMICAL NAME : Ether, bis(2-butoxyethyl) CAS REGISTRY NUMBER : 112-73-2 BEILSTEIN REFERENCE NO. : 1750713 REFERENCE : 4-01-00-02395 (Beilstein Handbook Reference) LAST UPDATED : 199806 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C12-H26-O3 MOLECULAR WEIGHT : 218.38 WISWESSER LINE NOTATION : 4O2O2O4 COMPOUND DESCRIPTOR : Reproductive Effector Primary Irritant SYNONYMS/TRADE NAMES : * Bis(2-butoxyethyl) ether * Butane, 1,1'-(oxybis(2,1-ethanediyloxy))bis- * Butyl diglyme * 2,2'-Dibutoxyethyl ether * Dibutyl carbitol * Dibutylether diethylenglykolu * Diethyleneglycoldibutyl ether * Diethylene glycol di-n-butyl ether * Ether, bis(butoxyethyl) * 5,8,11-Trioxapentadecane *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Open irritation test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg REACTION SEVERITY : Mild REFERENCE : UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/21/1967 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 4040 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 16 gm/kg SEX/DURATION : female 7-14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - stillbirth REFERENCE : EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,141,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2478 No. of Facilities: 71 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 2232 (estimated) No. of Female Employees: 113 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***