*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KN3500000
CHEMICAL NAME           : Ether, bis(nonafluorobutyl)
CAS REGISTRY NUMBER     : 308-48-5
BEILSTEIN REFERENCE NO. : 1809360
REFERENCE               : 4-02-00-00817 (Beilstein Handbook Reference)
LAST UPDATED            : 199803
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-F18-O
MOLECULAR WEIGHT        : 454.08
WISWESSER LINE NOTATION : FXFFXFFXFFXFFOXFFXFFXFFXFFF
SYNONYMS/TRADE NAMES :
   * Bis(perfluorobutyl) ether
   * Butane, 1,1'-oxybis(1,1,2,2,3,3,4,4,4-nonafluoro-
   * Diperfluorobutyl ether
   * Perfluorodibutylether
   * Perfluoro-n-dibutyl ether
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 80 gm/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,97,1982
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 49500 mg/m3/2H
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see TNICS*.  (Izdatel'stvo Meditsina, Moscow, USSR)  No.1-    1961-
   Volume(issue)/page/year: 15,101,1979
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4100 mg/m3/4H/17W-I
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Blood - pigmented or nucleated red blood cells
   Nutritional and Gross Metabolic - other changes
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see TNICS*.  (Izdatel'stvo Meditsina, Moscow, USSR)  No.1-    1961-
   Volume(issue)/page/year: 15,101,1979
 
                            *** END OF RECORD ***