*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KN9950000
CHEMICAL NAME           : Ether, ethyl heptafluoroisobutenyl
CAS REGISTRY NUMBER     : 360-58-7
BEILSTEIN REFERENCE NO. : 1789415
REFERENCE               : 4-01-00-03454 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C6-H5-F7-O
MOLECULAR WEIGHT        : 226.11
WISWESSER LINE NOTATION : FYFUYFXFO2&XFFF
SYNONYMS/TRADE NAMES :
   * Ether, ethyl tetrafluoro-2-(trifluoromethyl)propenyl
   * 1-Ethoxyperfluoroisobutylene
   * Ethyl heptafluoroisobutenyl ether
   * Ethyl perfluoroisobutenyl ethyl ether
   * Perfluoroisobutenylethyl ether
   * 1-Propene, 1-ethoxy-1,3,3,3-tetrafluoro-2-(trifluoromethyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 164 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 29(5),13,1964
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 46000 mg/m3
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see TNICS*.  (Izdatel'stvo Meditsina, Moscow, USSR)  No.1-    1961-
   Volume(issue)/page/year: 15,101,1979
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1274 mg/kg/30W-I
TOXIC EFFECTS :
   Behavioral - alteration of classical conditioning
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 29(5),13,1964
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1274 mg/kg/30W-I
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Cardiac - other changes
   Liver - fatty liver degeneration
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 29(5),13,1964
 
                            *** END OF RECORD ***