*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KQ9015000
CHEMICAL NAME           : Ethylamine, 2-chloro-N,N-dimethyl-
CAS REGISTRY NUMBER     : 107-99-3
BEILSTEIN REFERENCE NO. : 0605280
REFERENCE               : 4-04-00-00444 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C4-H10-Cl-N
MOLECULAR WEIGHT        : 107.60
WISWESSER LINE NOTATION : G2N1&1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Chloro(dimethylamino)ethane
   * beta-Chloroethyldimethylamine
   * N-(2-Chloroethyl)dimethylamine
   * (2-Chloroethyl)dimethylamine
   * Dimethylaminoethyl chloride
   * beta-(Dimethylamino)ethyl chloride
   * 2-Dimethylaminoethylchloride
   * Dimethyl(2-chloroethyl)amine
   * HN 1
   * Nitrogen half mustard
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHBUA9 Pharmaceutical Bulletin.  (Tokyo, Japan)  V.1-5, 1953-57.  For
   publisher information, see CPBTAL.  Volume(issue)/page/year: 1,297,1953
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   56,267,1985
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   56,267,1985
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 3600 umol/L
REFERENCE :
   GENTAE Genetics.  (Genetics Business Office, POB 64025, Baltimore, MD 21264)
    V.1-    1916-  Volume(issue)/page/year: 92,83,1979
 
TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intravaginal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 2 pph
REFERENCE :
   JIDEAE Journal of Investigative Dermatology.  (Williams & Wilkins Co., 428
   E. Preston St., Baltimore, MD 21202)  V.1-    1938- Volume(issue)/page/year:
   62,378,1974

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-reversion
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***