*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : KQ9015000 CHEMICAL NAME : Ethylamine, 2-chloro-N,N-dimethyl- CAS REGISTRY NUMBER : 107-99-3 BEILSTEIN REFERENCE NO. : 0605280 REFERENCE : 4-04-00-00444 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C4-H10-Cl-N MOLECULAR WEIGHT : 107.60 WISWESSER LINE NOTATION : G2N1&1 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * Chloro(dimethylamino)ethane * beta-Chloroethyldimethylamine * N-(2-Chloroethyl)dimethylamine * (2-Chloroethyl)dimethylamine * Dimethylaminoethyl chloride * beta-(Dimethylamino)ethyl chloride * 2-Dimethylaminoethylchloride * Dimethyl(2-chloroethyl)amine * HN 1 * Nitrogen half mustard *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 1,297,1953 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 nmol/plate REFERENCE : ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 56,267,1985 TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 100 nmol/plate REFERENCE : ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 56,267,1985 TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 3600 umol/L REFERENCE : GENTAE Genetics. (Genetics Business Office, POB 64025, Baltimore, MD 21264) V.1- 1916- Volume(issue)/page/year: 92,83,1979 TYPE OF TEST : DNA inhibition ROUTE OF EXPOSURE : Intravaginal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 2 pph REFERENCE : JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 62,378,1974 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-reversion EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***