*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KU6000000
CHEMICAL NAME           : Ethylene, 1-(p-amidinophenyl)-2,2-bis(p-anisyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 3688-80-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C23-H22-N2-O2.Cl-H
MOLECULAR WEIGHT        : 394.93
WISWESSER LINE NOTATION : MUYZR D1UYR DO1&R DO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzamidine, p-(2,2-bis(p-methoxyphenyl)vinyl)-, hydrochloride
   * 1,1-Bis(p-anisyl)-2-(p-guanylphenyl)ethylene hydrochloride
   * Ethylene, 1-(p-amidinophenyl)-2,2-bis(p-methoxyphenyl)-
   * MER-13
   * Stilbene, 4'-amidino-4-methoxy-alpha-(p-methoxyphenyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,362,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 99 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,362,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 23 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,362,1962
 
                            *** END OF RECORD ***