*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KV5330000
CHEMICAL NAME           : Ethylenediamine, N-(1-naphthyl)-, dihydrochloride
CAS REGISTRY NUMBER     : 1465-25-4
LAST UPDATED            : 199701
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C12-H14-N2.2Cl-H
MOLECULAR WEIGHT        : 259.20
WISWESSER LINE NOTATION : L66J BM2Z &GH 2
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-1-Naphthalenyl-1,2-ethanediamine dihydrochloride
   * N-(1-Naphthyl)ethylenediamine dihydrochloride
   * NCI-C03281
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 800 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 8(Suppl
   7),1,1986

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X3681
       No. of Facilities: 214 (estimated)
       No. of Industries: 5
       No. of Occupations: 7
       No. of Employees: 3452 (estimated)
       No. of Female Employees: 1660 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: Carcinogenicity-mouse/rat
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-168,79

 
                            *** END OF RECORD ***