*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KW2666700
CHEMICAL NAME           : Ethylene,
                          1-(p-fluorophenyl)-2-(p-methoxyphenyl)-2-phenyl-
CAS REGISTRY NUMBER     : 1237-20-3
BEILSTEIN REFERENCE NO. : 2563651
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H17-F-O
MOLECULAR WEIGHT        : 304.38
WISWESSER LINE NOTATION : FR D1UYR&R DO1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 1-(p-Fluorophenyl)-2-(p-methoxyphenyl)-2-phenylethylene
   * 1-(p-Methoxyphenyl)-1-phenyl-2-(p-fluorophenyl)ethylene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : male 10 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,606,1964
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 mg/kg
SEX/DURATION            : female 3 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 151,475,1964
 
                            *** END OF RECORD ***