*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KW4025000
CHEMICAL NAME : Ethylene glycol, diacetate
CAS REGISTRY NUMBER : 111-55-7
BEILSTEIN REFERENCE NO. : 1762308
REFERENCE : 4-02-00-00217 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 12
MOLECULAR FORMULA : C6-H10-O4
MOLECULAR WEIGHT : 146.16
WISWESSER LINE NOTATION : 1VO2OV1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* 1,2-Diacetoxyethane
* 1,2-Ethanediol diacetate
* Ethylene acetate
* Ethylene diacetate
* Ethylene diethanoate
* Glycol diacetate
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Mild
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N.
Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918-
Volume(issue)/page/year: 29,1363,1946
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury
Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/6/1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 90,338,1947
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 8480 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury
Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/6/1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 4940 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Gastrointestinal - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 23,259,1941
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 200 mg/m3/4H/17W-I
TOXIC EFFECTS :
Liver - other changes
Blood - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 52(11),86,1987
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-RUSSIA:STEL 30 mg/m3 JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M3113
No. of Facilities: 135 (estimated)
No. of Industries: 5
No. of Occupations: 9
No. of Employees: 1551 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M3113
No. of Facilities: 317 (estimated)
No. of Industries: 6
No. of Occupations: 7
No. of Employees: 1454 (estimated)
No. of Female Employees: 14 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***