*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LK8327500
CHEMICAL NAME : Flavone, 6-(N-diethylaminomethyl)-3-methyl-
CAS REGISTRY NUMBER : 15686-60-9
BEILSTEIN REFERENCE NO. : 1321810
REFERENCE : 5-18-11-00530 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C21-H23-N-O2
MOLECULAR WEIGHT : 321.45
WISWESSER LINE NOTATION : T66 BO EVJ CR& D1 H1N2&2
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 6-((Diethylamino)methyl)-3-methyl-4H-benzopyran-4-one
* 6-(N-Diethylaminomethyl)-3-methylflavone
* Flavamine
* 3-Methyl-6-(N-diaethylaminomethyl)-flavon
* REC 7-0052
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 145 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - coma
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 9,693,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 109 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - coma
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 9,693,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 26 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - coma
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 9,693,1959
*** END OF RECORD ***