*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LL5600000
CHEMICAL NAME           : Fluoren-2-amine, N-methyl-
CAS REGISTRY NUMBER     : 63019-68-1
BEILSTEIN REFERENCE NO. : 2720352
REFERENCE               : 4-12-00-03371 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H13-N
MOLECULAR WEIGHT        : 195.28
WISWESSER LINE NOTATION : L B656 HHJ EM1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 2-Fluorenylmonomethylamine
   * 2-Methylaminofluorene
   * N-Monomethyl-2-aminofluorene
   * 2-Monomethylaminofluorene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1260 mg/kg/24W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   6,89,1952
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4300 mg/kg/47W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   JBCHA3 Journal of Biological Chemistry.  (428 E. Preston St., Baltimore, MD
   21202)  V.1-    1905-  Volume(issue)/page/year: 221,845,1956
 
                            *** END OF RECORD ***