*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LM5200000
CHEMICAL NAME           : Fluorescein, 4',5'-dibromo-
CAS REGISTRY NUMBER     : 596-03-2
BEILSTEIN REFERENCE NO. : 0057189
REFERENCE               : 5-19-06-00462 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C20-H10-Br2-O5
MOLECULAR WEIGHT        : 490.12
WISWESSER LINE NOTATION : T C666 BO EVJ DE IR BVQ& MQ NE
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Acid Orange 11
   * C.I. 45370:1
   * C.I. Solvent Red 72
   * D&C Orange No. 5
   * 4',5'-Dibromofluororescein
   * Eosinic acid
   * Japan Orange 201
   * Solvent Red 72
   * Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one,  
   4',5'-dibromo-3',6'-dihydroxy-
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15556 mg/kg/21D-C
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes in urine composition
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Related to Chronic Data - changes in ovarian weight
REFERENCE :
   TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho.  Annual Report of Tokyo
   Metropolitan Research Laboratory of Public Health.  (Tokyo-toritsu Eisei
   Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1-
      1949/50-  Volume(issue)/page/year: 27,145,1976
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ng/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 1,116,1979

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T1904
       No. of Facilities: 237 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 6161 (estimated)
       No. of Female Employees: 474 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8792
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***