*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LQ4740000
CHEMICAL NAME           : Formhydroxamic acid
CAS REGISTRY NUMBER     : 4312-87-2
BEILSTEIN REFERENCE NO. : 1698504
REFERENCE               : 4-02-00-00083 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C-H3-N-O2
MOLECULAR WEIGHT        : 61.05
WISWESSER LINE NOTATION : VHMQ
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Formamide, N-hydroxy-
   * Formhydroxamsaeure
   * Formohydroxamic acid
   * Formylhydroxamic acid
   * Formylhydroxylamine
   * Hydroxylamine, N-formyl-
   * N-Hydroxyformamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 570 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APEPA2 Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle
   Pathologie.  (Berlin, Ger.) V.254-263, 1966-69.  For publisher information,
   see NSAPCC.  Volume(issue)/page/year: 257,296,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 570 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 29,225,1973
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : female 13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 26(3),9A,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   APEPA2 Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle
   Pathologie.  (Berlin, Ger.) V.254-263, 1966-69.  For publisher information,
   see NSAPCC.  Volume(issue)/page/year: 257,296,1967
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 680 mg/kg
SEX/DURATION            : female 13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 33,69C,1986
 
                            *** END OF RECORD ***