*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LS7083000
CHEMICAL NAME           : beta-D-Fructopyranose,
                          2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
CAS REGISTRY NUMBER     : 97240-79-4
BEILSTEIN REFERENCE NO. : 5988957
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C12-H21-N-O8-S
MOLECULAR WEIGHT        : 339.40
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
   * McN-4853
   * RWJ-17021-000
   * Topiramate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   14,342,1989
 
                            *** END OF RECORD ***