*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LT1950000
CHEMICAL NAME           : Fumaric acid, iron(2+) salt (1:1)
CAS REGISTRY NUMBER     : 141-01-5
LAST UPDATED            : 199701
DATA ITEMS CITED        : 15
MOLECULAR FORMULA       : C4-H2-O4.Fe
MOLECULAR WEIGHT        : 169.91
WISWESSER LINE NOTATION : OV1U1VO &-FE-
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * 2-Butenedioic acid (E)-, iron(2+) salt (1:1)
   * Cpiron
   * Erco-Fer
   * Ercoferro
   * Feostat
   * Feroton
   * Ferrofume
   * Ferronat
   * Ferrone
   * Ferrotemp
   * Ferrous fumarate
   * Fersamal
   * Firon
   * Fumafer
   * Fumar
   * Fumar-F
   * Fumiron
   * Galfer
   * Hemoton
   * Ircon
   * Iron fumarate
   * One-iron
   * Palafer
   * Toleron
   * Tolferain
   * Tolifer
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - nausea or vomiting
REFERENCE :
   HUTODJ Human Toxicology.  (Macmillan Press Ltd., Houndmills, Basingstoke,
   Hants., RG 21 2XS, UK) V.1-    1981-  Volume(issue)/page/year: 7,281,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3850 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,683,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 185 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,683,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,683,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1570 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AJMSA9 American Journal of the Medical Sciences.  (Slack Inc., 6900 Grove
   Rd., Thorofare, NJ 08086) New series: V.1-    1841- Volume(issue)/page/year:
   241,296,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 480 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AJMSA9 American Journal of the Medical Sciences.  (Slack Inc., 6900 Grove
   Rd., Thorofare, NJ 08086) New series: V.1-    1841- Volume(issue)/page/year:
   241,296,1961

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 1 mg(Fe)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,138,1971

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80414
       No. of Facilities: 129 (estimated)
       No. of Industries: 2
       No. of Occupations: 9
       No. of Employees: 9131 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80414
       No. of Facilities: 429 (estimated)
       No. of Industries: 3
       No. of Occupations: 18
       No. of Employees: 3859 (estimated)
       No. of Female Employees: 1728 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***