*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LQ0692500
CHEMICAL NAME           : Formamide,
                          N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-(((be
                          nzoyloxy)methyl)thio)-
                          4-hydroxy-1-methyl-1-butenyl)-, hydrochloride
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-N4-O4-S.Cl-H
MOLECULAR WEIGHT        : 453.00
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzoyloxymethyl-thiamine hydrochloride
   * BT 851 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   122,27,1983
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   122,27,1983
 
                            *** END OF RECORD ***