*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LQ0699000
CHEMICAL NAME           : Formamide,
                          N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydro
                          xy-1-methyl-2- (propyldithio)-1-butenyl)-
CAS REGISTRY NUMBER     : 59-58-5
LAST UPDATED            : 199706
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C15-H24-N4-O2-S2
MOLECULAR WEIGHT        : 356.55
WISWESSER LINE NOTATION : T6N CNJ B1 DZ E1NVHY1&UY2QSS3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alinamin
   * Aliton
   * Arinamine
   * Dithiopropylthiamine
   * Nervilon
   * Neurvita
   * Nevriton
   * Nuvelbi V.C.A.
   * Prosulthiamine
   * Prosultiamine
   * Thiamine propyl disulfide
   * Thiamin propyl disulfide
   * Tiotiamina
   * Tiovit-B(sub 1)
   * Tipidi
   * TPD
   * Vitamin B(sub 1) propyl disulfide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,724,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,724,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,724,1982
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37500 mg/kg/15D-I
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   INDRBA Indian Drugs.  (Indian Drugs Manufacturers' Assoc., 102B, Poonam
   Chambers, Dr. A. B. Rd., Worli, Bombay 400 018, India)  V.1-    1963-
   Volume(issue)/page/year: 12,13,1974/1975
 
                            *** END OF RECORD ***