*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LT8535000
CHEMICAL NAME           : 2-Furanacrylamide, N-isopropyl-5-nitro-
CAS REGISTRY NUMBER     : 1951-56-0
LAST UPDATED            : 199410
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C10-H12-N2-O4
MOLECULAR WEIGHT        : 224.24
WISWESSER LINE NOTATION : T5OJ BNW E1U1VMY1&1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * F30066
   * Furapromidium
   * N-Isopropyl-5-nitro-2-furanacrylamide
   * N-(Isopropyl)-3-(5-nitro-2-furanyl)-2-propenamide
   * N-Isopropyl-3-(5-nitro-2-furyl)-acrylamide
   * N-(1-Methylethyl)-3-(5-nitro-2-furanyl)-2-propenamide
   * 2-Propenamide, N-(1-methylethyl)-3-(5-nitro-2-furanyl)-
   * S30066
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 14 nmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,37,1977
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Neurospora crassa
DOSE/DURATION           : 200 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 53,297,1978
 
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 125 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,37,1977
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 120 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,37,1977

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: N crassa-forward mutation; N
   crassa-reversion
   
   EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
   
   EPA GENETOX PROGRAM 1988, Positive: V79 cell culture-gene mutation
   
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae gene conversion

 
                            *** END OF RECORD ***