*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LU3488500
CHEMICAL NAME           : 2(5H)-Furanone,
                          5-((2-chlorophenyl)hydroxymethyl)-4-methoxy-,
                          (R*,S*)-
CAS REGISTRY NUMBER     : 112856-44-7
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H11-Cl-O4
MOLECULAR WEIGHT        : 254.68
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AO 33
   *   (5R*)-5-((alpha-S*)-o-Chloro-alpha-hydroxybenzyl)-4-methoxy-2(5H)-furano
     ne
   * (R*,S*)-5-((2-Chlorophenyl)hydroxymethyl)-4-methoxy-2(5H)-furanone
   * Losigamone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,995,1990
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,995,1990
 
                            *** END OF RECORD ***