*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LV2150000
CHEMICAL NAME           : 4H-Furo(3,2-b)indole-2-carboxamide,
                          4-methyl-N-(3-piperidinopropyl)-6-(trifluoromethyl)-
CAS REGISTRY NUMBER     : 73356-67-9
BEILSTEIN REFERENCE NO. : 5647884
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H24-F3-N3-O2
MOLECULAR WEIGHT        : 407.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * FI-302
   *   4-Methyl-N-(3-piperidinopropyl)-6-(trifluoromethyl)-4H-furo(3,2-b)indole
     -2-carboxamide
   *   N-(3-Piperidinopropyl)-4-methyl-6-trifluoromethylfuro(3,2-b)indole-2-car
     boxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   8,477,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 332 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   8,477,1985
 
                            *** END OF RECORD ***