*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LW5950000
CHEMICAL NAME           : Galacturonic acid, compd. with
                          alpha-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidineme
                          thanol
CAS REGISTRY NUMBER     : 28371-10-0
OTHER CAS REGISTRY NOS. : 7681-28-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-N2-O2.C6-H10-O7
MOLECULAR WEIGHT        : 518.62
WISWESSER LINE NOTATION : T66 BNJ HO1 EYQ- DT66 A B CNTJ A1U1 &621 
                          VHYQYQYQYQVQ -ABBA &622
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cardioquin
   * Galactoquin
   * Galacturonic acid, compd. with (9S)-6'-methoxycinchonan-9-ol (1:1)
   * Galacturonic acid, compd. with quinidine
   * Naticardina
   * Quinidine galacturonate
   * Quinidine polygalacturonate
   * 2-Quinuclidinemethanol, alpha-(6-methoxy-4-quinolyl)-5-vinyl-,  
   galacturonate (salt)
   * Sineflutter
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3200 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - other changes
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 9,97,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2680 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
   Gastrointestinal - other changes
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 9,97,1959
 
                            *** END OF RECORD ***