*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LW5952100
CHEMICAL NAME : Galanthamine
CAS REGISTRY NUMBER : 357-70-0
BEILSTEIN REFERENCE NO. : 0093736
REFERENCE : 4-27-00-02184 (Beilstein Handbook Reference)
LAST UPDATED : 199706
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C17-H21-N-O3
MOLECULAR WEIGHT : 287.39
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 6H-Benzofuro(3a,3,2-ef)(2)benzazepin-6-ol,
4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-
* Galantamin
* Galantamine
* Jilkon
* Lycoremin
* Lycoremine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 22900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #5177082
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 37,689,1994
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 14 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4550113
*** END OF RECORD ***