*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LY4300000
CHEMICAL NAME           : Germacra-1(10),4,11(13)-trien-12-oic acid,
                          6-alpha,8-alpha,15-trihydroxy-, 12,6-lactone,
                          8-(3,4-dihydroxy-2-methylenebutyrate)
CAS REGISTRY NUMBER     : 24394-09-0
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H26-O
MOLECULAR WEIGHT        : 282.46
SYNONYMS/TRADE NAMES :
   * Cnicin
   * Cnicine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 452 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLMEAA Planta Medica.  (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
   1, Fed. Rep. Ger.) V.1-    1953-  Volume(issue)/page/year: 53,247,1987
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLMEAA Planta Medica.  (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
   1, Fed. Rep. Ger.) V.1-    1953-  Volume(issue)/page/year: 29,179,1976
 
                            *** END OF RECORD ***