*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ4296200
CHEMICAL NAME           : D-Glucitol, 1-deoxy-1-(methylamino)-,
                          3-(acetylamino)-5-(((2-hydroxyethyl)amino)carbonyl)
                          2,4,6-triiodobenzoate (salt), mixt. with
                          3-(acetylamino)-5-(((2-hydroxyethyl)amino)
                          carbonyl)-2,4,6-triiodobenzoic acid compd. with
                          2-aminoethanol (1:1)
CAS REGISTRY NUMBER     : 37244-86-3
LAST UPDATED            : 198308
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H11-I3-N2-O5.C12-H11-I3-N2-O5.C7-H17-N-O5.C2-H7-N
                          -O
MOLECULAR WEIGHT        : 1544.25
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AG. 5895
   * Vasobrix 32
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11500 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 26,595,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18900 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 26,595,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15100 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 26,595,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 26,595,1971
 
                            *** END OF RECORD ***