*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : LZ4300000 CHEMICAL NAME : D-Glucitol, 1-deoxy-1-(methylamino)-, 3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt) mixed with 3,5-bis(acetylamino)-2,4,6-triiodobenzoic acid monosodium salt CAS REGISTRY NUMBER : 8064-12-8 OTHER CAS REGISTRY NOS. : 19121-26-7 39468-26-3 51745-36-9 63705-10-2 78171-11-6 LAST UPDATED : 199512 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C11-H9-I3-N2-O4.C11-H8-I3-N2-O4.C7-H17-N-O5.Na MOLECULAR WEIGHT : 1445.07 WISWESSER LINE NOTATION : 1VMR BI DI FI CVQ EMV1 &1VMR BI DI FI CVO EMV1 &Q1YQYQYQYQ1M1 &-NA- COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Angiovist 292 * Angiovist 370 * Diatrizoate de sodium et de methylglucamine * Hypaque 76 * Hypaque 85 * Hypaque-M * Hypaque 75M * MD 76 * Meglumine sodium amidotrizoate * Penografin-76 * Radioselectan 76 * Radioselectan forte * Renografin 60 * Renografin 76 * Renovist II * Sodium meglumine diatrizoate * Sodium methylglucamine diatrizoate * Triombrast * Triyosom C * Urografin * Urografin 60 * Urografin 76 * Urombrine 420 * Uropolinum * Urovison * Verografin * Verographin * Visotrast *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 29200 ug/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - chronic pulmonary edema REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 12(Suppl 1),11,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 19 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 26,921,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 11500 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,595,1971 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 22525 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FMTYA2 Farmatsiya (Sofia). (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1951- Volume(issue)/page/year: 32(3),18,1983 *** END OF RECORD ***