*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ5055000
CHEMICAL NAME           : D-Gluconamide,
                          N,N'-(2,4,6-triiodo-5-((methylamino)carbonyl)-1,3-phe
                          nylene)bis-
CAS REGISTRY NUMBER     : 63941-74-2
BEILSTEIN REFERENCE NO. : 3026504
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C20-H28-I3-N3-O13
MOLECULAR WEIGHT        : 899.21
WISWESSER LINE NOTATION : Q1YQYQYQYQVMR BI DI FI CVM1 EMVYQYQYQYQ1Q
SYNONYMS/TRADE NAMES :
   * 3,5-Bis-D-gluconamido-2,4,6-triiodo-N-methylbenzamide
   * Ioglucomide
   *   N,N'-(2,4,6-Triiodo-5-((methylamino)carbonyl)-1,3-phenylene)bis-D-glucon
     amide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15600 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADLAX Radiology.  (Radiological Soc. of North America, 20th & Northampton
   Sts., Easton, PA 18042) V.1-    1923-  Volume(issue)/page/year: 140,713,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 365 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - anticonvulsant
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RADLAX Radiology.  (Radiological Soc. of North America, 20th & Northampton
   Sts., Easton, PA 18042) V.1-    1923-  Volume(issue)/page/year: 140,713,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16200 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - anticonvulsant
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADLAX Radiology.  (Radiological Soc. of North America, 20th & Northampton
   Sts., Easton, PA 18042) V.1-    1923-  Volume(issue)/page/year: 140,713,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 22700 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - anticonvulsant
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADLAX Radiology.  (Radiological Soc. of North America, 20th & Northampton
   Sts., Easton, PA 18042) V.1-    1923-  Volume(issue)/page/year: 140,713,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 23800 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - anticonvulsant
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RADLAX Radiology.  (Radiological Soc. of North America, 20th & Northampton
   Sts., Easton, PA 18042) V.1-    1923-  Volume(issue)/page/year: 140,713,1981
 
                            *** END OF RECORD ***