*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ6572600
CHEMICAL NAME           : beta-D-Glucopyranuronic acid,
                          1-deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrim
                          idinyl)-
CAS REGISTRY NUMBER     : 66048-45-1
LAST UPDATED            : 199309
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H11-F-N2-O8
MOLECULAR WEIGHT        : 306.23
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acido  
   1-deossi-1-(3,4-diidro-2,4-diosso-5-fluoro-1(2H)pirimidinil)glucopiranur  
   onico
   *   1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-beta-D-gluc
     opyranuronic acid
   *   1-Deoxy-1-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydro-1-pyrimidinyl)-beta-D-g
     lucopyranuronic acid
   * 5-Fluouracil N-glucuronide
   * 5-FU N-glucuronide
   * FU-N-G
   * MG 6758
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1883 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   118,721,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   69,283,1978
 
                            *** END OF RECORD ***