*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ9700000
CHEMICAL NAME           : Glutamic acid, L-
CAS REGISTRY NUMBER     : 56-86-0
LAST UPDATED            : 199706
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C5-H9-N-O4
MOLECULAR WEIGHT        : 147.15
WISWESSER LINE NOTATION : QVYZ2VQ -L
COMPOUND DESCRIPTOR     : Mutagen
                          Human
SYNONYMS/TRADE NAMES :
   * Aciglut
   * alpha-Aminoglutaric acid
   * L-2-Aminoglutaric acid
   * 2-Aminopentanedioic acid
   * 1-Aminopropane-1,3-dicarboxylic acid
   * Glusate
   * Glutacid
   * Glutamic acid
   * L-Glutamic acid
   * alpha-Glutamic acid
   * D-Glutamiensuur
   * Glutaminic acid
   * L-Glutaminic acid
   * Glutaminol
   * Glutaton
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 71 mg/kg
TOXIC EFFECTS :
   Behavioral - headache
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   163,826,1969
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human
DOSE/DURATION           : 117 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   AJMSA9 American Journal of the Medical Sciences.  (Slack Inc., 6900 Grove
   Rd., Thorofare, NJ 08086) New series: V.1-    1841- Volume(issue)/page/year:
   214,281,1947
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >30 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 48A,42,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >2300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 48A,42,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 372,75,1996

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 10 mg/m3 JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80420
       No. of Facilities: 446 (estimated)
       No. of Industries: 6
       No. of Occupations: 13
       No. of Employees: 10592 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80420
       No. of Facilities: 915 (estimated)
       No. of Industries: 10
       No. of Occupations: 27
       No. of Employees: 11240 (estimated)
       No. of Female Employees: 5754 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***