*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MA1230000
CHEMICAL NAME           : Glutamic acid,
                          N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b
                          enzoyl)-, dibutyl ester, L-(+)-
CAS REGISTRY NUMBER     : 50602-77-2
BEILSTEIN REFERENCE NO. : 1201115
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C28-H38-N8-O5
MOLECULAR WEIGHT        : 566.74
WISWESSER LINE NOTATION : T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVO4&2VO4
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Dbmtx
   * Dibutyl methotrexate
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   25,1943,1976
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   25,1943,1976
 
                            *** END OF RECORD ***