*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : MA1247500 CHEMICAL NAME : Glutamic acid, N-(p-(((2,4-diamino-6-quinazolinyl)methyl)amino)benzo yl)-, L- CAS REGISTRY NUMBER : 18921-68-1 LAST UPDATED : 198312 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H22-N6-O5 MOLECULAR WEIGHT : 438.49 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * CB 3702 * Deazaaminopterin * Deazaminopterin * L-N-(p-(((2,4-Diamino-6-quinazolinyl)methyl)amino)benzoyl)glutamic acid * NCS 529860 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 65 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2709506 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 65 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2709506 *** END OF RECORD ***